周翔天 瞿佳
【摘要】 近视是一种临床常见的屈光不正，其发病率日益增高，目前被认为是一类全球性的健康问题，因此进行近视机制的临床和基础研究对于探索近视的预防和治疗方案具有重大的意义。屈光发育是一个多因素参与的复杂过程，根据流行病学类和临床干预研究结果发现与近视发生发展相关的因素，利用近视动物模型和各种各样的实验方法，明确其因果关系，并进一步对近视的发生、发展机制进行更加深入广泛的研究，从而为今后临床上进行安全有效的近视干预奠定基础。
【关键词】 近视； 临床研究； 基础研究
DOI：10.3760/cma.j.issn.1674-845X.2014.06.001
作者单位：325027
通信作者：瞿佳，Email：jqu@wz.zj.cn
The clinical and basic study of myopia mechanism Zhou Xiangtian， Qu Jia. Eye Hospital of Wenzhou Medical University， Wenzhou 325027， China
Corresponding author：Qu Jia，Email：jqu@wz.zj.cn
【Abstract】 As one of the most popular refractive errors in clinic， the rising incidence of myopia is now considered as a global health problem， thus clinical and basic studies of myopia mechanism greatly contribute to the prevention and treatment of myopia. Refractive development is a complex process which many factors are involved in. These factors related to myopia development are explored by epidemiological and clinical intervention studies， then they are further investigated on myopia animal models or by various experimental methods to determine their causal relationship with myopia and further clarify the development mechanism of myopia， which lay the foundation for a safe and effective intervention of myopia clinically.
【Key words】 Myopia； Clinical study； Basic study 中华眼视光学与视觉科学